Transperineal Biopsy Workflow

Efficient Pre-Biopsy Planning with MRI Preparation

Using Koelis’ ProMap Lite^™ Application:

• The prostate is segmented
• Suspicious lesions are defined
• Segmented MRIs are transferred to the Koelis Trinity® platform

Precision 3D Biopsy Scan and Guidance

3D Ultrasound Scan

• Prostate is scanned using our unique 3D ultrasound technology
• Motorized sensor rotates the ultrasound array within the probe
• 3D prostate scan is recorded in less than 3 seconds

Biopsy Guidance

• A 3D model of the prostate is generated
• Segmented MRI is elastically fused to the ultrasound image
• A reference volume of the prostate is displayed with MRI targets

3D Cartography

• Biopsy of the prostate is performed
• An updated 3D ultrasound is acquired with each pass of the biopsy needle
• Location of each biopsy core is transferred to the reference volume
• KOELIS Trinity® builds a precise 3D map of the biopsy procedure

Post-Biopsy Review, Re-Biopsy and Treatment

• Post-biopsy, the 3D map can be reviewed on the Trinity
• This map guides subsequent biopsies and treatment programs
• 3D map aids in future treatments such as prostate ablation, IRE, HIFU and cryotherapy

 

Comparing Transperineal and Transrectal Biopsy Approaches

 

KOELIS Trinity® provides flexibility to perform targeted transperineal or transrectal or MRI/ultrasound fusion guided biopsies. While the majority of biopsies are conducted transrectally, transperineal biopsy has grown in popularity and offers a number of benefits including:

• Reduced risk of infection
• Access to anterior targets
• Orientation similar to focal therapies conducted via the perineum
• Less discomfort for the patient during the procedure
• Improved detection of clinically significant prostate cancer

The KOELIS Trinity® fusion biopsy system is proven to be more reliable than other fusion platforms. Our proprietary Organ-Based Tracking (OBT) technology compensates for patient and prostate movement, so physicians can be certain they receive an accurate image of the prostate during biopsy.

¹ Bajeot et al. Managing Discordant Findings Between Multiparametric Magnetic Resonance Imaging and Transrectal Magnetic Resonance Imaging–directed Prostate Biopsy—The Key Role of Magnetic Resonance Imaging–directed Transperineal Biopsy. European Urology Oncology, 2021. https://pubmed.ncbi.nlm.nih.gov/34154979/

² Jacewicz et al. Cancer Detection Rates in Targeted Transperineal MRI-TRUS Elastic Fusion-guided Prostate Biopsies Performed Under Local Anesthesia. Anticancer Res, 2021. https://pubmed.ncbi.nlm.nih.gov/34475059/

³ Jacewicz et al. Multicenter transperineal MRI-TRUS fusion guided outpatient clinic prostate biopsies under local anesthesia. Urol Oncol, 2021 https://pubmed.ncbi.nlm.nih.gov/33257219/